Sports
Louisville and Michigan State Clash in NCAA Tournament Round Two
Louisville Cardinals will face the Michigan State Spartans in the second round of the 2026 NCAA Tournament on Saturday. The Louisville Cardinals defeated South Florida 83-79, and the Michigan State Spartans defeated North Dakota State 92-67 in the prior round on Thursday.
The Louisville Cardinals and the Michigan State Spartans will compete at the KeyBank Center in Buffalo, New York. The Cardinals, with a 24-10 record, finished sixth in the ACC with an 11-7 record. Louisville has a 3-6 record against ranked teams. Michigan State tied for second in the Big Ten standings with a 15-5 record, holding an overall record of 26-7. The Spartans are 5-4 against ranked teams this season. SportsLine's model offers college basketball picks for Saturday's second-round matchup.
Key Facts
- The Louisville Cardinals will play the Michigan State Spartans in the second round.
- The game will be held at KeyBank Center in Buffalo.
- Louisville defeated South Florida 83-79.
- Michigan State defeated North Dakota State 92-67.
- Louisville is 24-10 overall and finished 11-7 in the ACC.
- Michigan State is 26-7 overall and finished 15-5 in the Big Ten.
- The Louisville vs. Michigan State over/under for total points scored is 151.
- Louisville is favoured by 5 points.
Primary Source
Research Sources
- CBS Sports — Louisville vs. Michigan State prediction, odds, line, spread, time: 2026 NCAA Tournament picks from proven model - CBS Sports